Nephroprotective Effect of Corn Silk: A Review on its Mechanism of Action and Safety Evaluation

Pragati Singh, Jyoti Singh, Prasad Rasane, Sawinder Kaur, Vikas Nanda and Sezai Ercisli


The traditional and indigenous methods of treating diseases have been very common since time long. The COVID 19 outbreak made people more inclined towards the use of herbs and plants more than drugs and pharmaceuticals. Corn silk which is commonly dumped as agricultural waste can also be used for some remedial purpose. Corn silk is the long silky threads that develops on the cob of corn. Renal health is an important aspect of overall well-being. Kidney diseases are usually caused by secondary or indirect conditions that stress the kidneys and gives extra load on it. The antioxidant properties which scavenge the free radicals and protects the cells of the kidney from oxidative stress, the anti-inflammatory properties, diuretic properties which helps promote urine production and thus reducing the load on kidneys, the spasmodic effect which help relax the urinary tract and improve urine flow, and uric acid lowering property of corn silk are the combined causes that makes it a potential nutraceutical for treating kidney ailments. The aim of this review paper is to thoroughly access the scientific research and to emphasise the potential advantages of corn silk in preventing and treating kidney ailments. The mechanism of action and experimental evidence pertaining to the positive outcomes of corn silk on kidney function is examined in this review. By providing a comprehensive overview this review aims increase comprehension of nephroprotective functions of corn silk and serve as a roadmap for future research and therapeutic intervention in various kidney diseases.

Published on: October 24, 2023
doi: 10.17756/jfcn.2023-s1-006
Citation: Singh P, Singh J, Rasane P, Kaur S, Nanda V, et al. 2023. Nephroprotective Effect of Corn Silk: A Review on its Mechanism of Action and Safety Evaluation. J Food Chem Nanotechnol 9(S1): S28-S35.